Caloric Restriction Mimetic 2-deoxy-glucose Antagonizes Doxorubicin- Induced Cardiomyocyte Death through Multiple Mechanisms

نویسندگان

  • Kai Chen
  • Xianmin Xu
  • Satoru Kobayashi
  • Derek Timm
  • Tyler Jepperson
  • Qiangrong Liang
چکیده

CALORIC RESTRICTION MIMETIC 2-DEOXY-GLUCOSE ANTAGONIZES DOXORUBICININDUCED CARDIOMYOCYTE DEATH THROUGH MULTIPLE MECHANISMS Kai Chen, Xianmin Xu, Satoru Kobayashi, Derek Timm, Tyler Jepperson, Qiangrong Liang* Cardiovascular Health Research Center, Sanford Research/USD, Sioux Falls, South Dakota 57104 Running title: 2-Deoxy-Glucose Inhibits Doxorubicin-induced Cardiomyocyte Death *Address Correspondence: Qiangrong Liang, Cardiovascular Health Research Center, Sanford Research/USD, University of South Dakota Sanford School of Medicine, Sioux Falls, SD 57104. Tel. 605-312-6304; Fax. 605-312-6071; E-mail: [email protected]

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تاریخ انتشار 2011